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Published byHerman Budiono Modified over 6 years ago
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To Make a Long Spindle Short: Nuclear Envelope Breakdown during Meiosis
Joseph M. Varberg, Sue L. Jaspersen Cell Reports Volume 23, Issue 4, Pages (April 2018) DOI: /j.celrep Copyright © 2018 The Author(s) Terms and Conditions
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Figure 1 Mechanisms of Spindle Disassembly in Fission Yeast Meiosis
Spindle disassembly during meiosis I is triggered by Imp1-dependent transport (green spheres) of spindle disassembly factors (orange spheres) in wild-type (WT) cells. Spindle disassembly in meiosis II is Imp1 independent and facilitated by vNEBD (dotted blue lines) where nuclear and cytoplasmic contents mix. The timing of Imp1-dependent and Imp1-independent spindle disassembly affects the ploidy and viability of the four haploid meiotic products, as shown through analysis of the indicated mutants. Cell Reports , DOI: ( /j.celrep ) Copyright © 2018 The Author(s) Terms and Conditions
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