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Hypersensitivity reactions to chemotherapy: Outcomes and safety of rapid desensitization in 413 cases  Mariana C. Castells, MD, PhD, Nichole M. Tennant,

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Presentation on theme: "Hypersensitivity reactions to chemotherapy: Outcomes and safety of rapid desensitization in 413 cases  Mariana C. Castells, MD, PhD, Nichole M. Tennant,"— Presentation transcript:

1 Hypersensitivity reactions to chemotherapy: Outcomes and safety of rapid desensitization in 413 cases  Mariana C. Castells, MD, PhD, Nichole M. Tennant, BA, David E. Sloane, MD, F. Ida Hsu, MD, Nora A. Barrett, MD, David I. Hong, MD, Tanya M. Laidlaw, MD, Henry J. Legere, MD, Samridhi N. Nallamshetty, MD, Ross I. Palis, MD, Jayanti J. Rao, MD, Suzanne T. Berlin, DO, Susana M. Campos, MD, Ursula A. Matulonis, MD  Journal of Allergy and Clinical Immunology  Volume 122, Issue 3, Pages (September 2008) DOI: /j.jaci Copyright © 2008 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 Frequency of symptoms and signs during initial HSRs.
Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2008 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3 Fig 2 A, Number and severity of reactions during desensitization. A mild reaction was defined as absence of chest pain, changes in blood pressure, dyspnea, oxygen, desaturation, or throat tightness. A severe reaction included 1 of these. B, Desensitization step at which reactions occurred (total number of reactions = 180). C, Desensitization course at which reactions recurred (total number of reactions = 135 [111 mild and 24 severe]). Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2008 American Academy of Allergy, Asthma & Immunology Terms and Conditions


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