1. 1. 1. Microscope Development A. Definition B. History of Cell Biology INTRODUCTION I. Cell Cell Biology

2. a. Zacharias Janssen, 1595 first light microscope c. Robert Hooke, 1665 coined Cellulae d. Anton VanLeeuwenhoek, 1672 Homunculus andAnimalcules b. Galileo, 1609 focusing device

3. e. Charles Spencer, 1850s first compound scope f. Max Knot & Ernst Ruska, 1933 first electron microscope

4. 2. 2. Basics of Cell Theory

5. a. Robert Dutrochet, 1824 plants made of cells c. Theodor Schwann & Matthias Schleiden, 1839 Cell Theory i. The cell is the basic unit in living organisms. b. Robert Brown, 1824 Brownian motion & the nucleus ii. The cell is the building block of organisms.

6. e. Rudolph Virchow, 1859 Spontaneous Generation d. J. Purkinji, 1840s coined the term protoplasm iii. Cells arise from preexisting cells.

7. 3. 3. Cellular Control

8. a. Karl VanNageli, 1846 plant cells derived from direct division of maternal cells d. Frank Meischer, 1871 proposed nuclein material of nucleic acids b. E. Strausburger & Walter Fleming, 1840s directions for growth and division of cells contained in the nucleus c. Gregor Mendel, 1860s proposed a hereditary molecule was responsible for expression of traits in an organism

9. d. Robert Altmann, 1889 purified nucleic acids into purine and pyrimidine bases DNA in all cells, while RNA variable e. James Watson & Francis Crick, 1953 summarized research and built model of DNA

10. A. Highly Organized II. Characteristics of Life

11. Molecules Biosphere

12. Molecules Biosphere Figure 1.3

13. B. Transform Energy

14. Bioenergetics

15. Figure 1.4

16. C. Reproduce

17. Variation in Nature

18. Variation in Nature

19. Variation in Nature

20. D. Grow & Develop

21. Stages and Accomplishments

22. Stages and Accomplishments

23. Stages and Accomplishments

24. E. Irritable & Adaptable

25. Daily Adjustments vs. Population Changes

26. Daily Adjustments vs. Population Changes

27. F. Practice Homeostasis

28. Balanced against Change

29. Balanced against Change

30. Negative vs. Positive Mechanisms

31. Negative vs. Positive Mechanisms Figure 1.11 Figure 1.12

32. A. Size Limits III. Types of Cells

33. Surface Area vs. Volume Dilemma Figure 6.2

34. Surface Area vs. Volume Dilemma Figure 6.2

35. B. Prokaryotes 1. Size Limits

38. 2. Characteristics

41. C. Eukaryotes 1. Size Limits

43. 2. Characteristics

44. Figure 6.9 Figure 6.9

45. Figure 6.9

46. D. Viruses 1. Characteristics

47. The parts == protein (capsid, landing gear, and injector) surrounding a nucleic acid core (genome = can be DNA or RNA) Figure 18.4

48. 2. Strategies

49. 1. Lytic = inject, insert, take over, direct, and destroy Figure 18.6

50. 2. Lysogenic = same except hide for a time then lytic Figure 18.7

51. D. Viroids & Prions 1. What?

52. IV. Cell Biology Related Topics

53. Thats all for now folks!!!!