1. Optimizing Targeted Therapy for HER2-Positive Advanced Breast Cancer: Considerations for Previously Treated Disease

3. Program Goals

4. Introduction: Selecting Anti-HER2 Therapy

5. New Agents and Optimal Regimens

8. Case 1: Initial Treatment for First Recurrence

10. Screening for Brain Metastases

11. Case 1. Treatment of HER2+ MBC After Progression on First-Line Therapy

12. Second-Line Treatment Options for HER2+ MBC Pre-T-DM1

13. Case 1: T-DM1 for Progressive, Previously Treated HER2+ MBC

14. Case 1: Previously Treated HER2+ MBC Progression on T-DM1

15. Hormone-Positive HER2+ MBC

16. Progression on T-DM1 Treatment Options

18. First-Line Treatment With T-DM1 vs Trastuzumab + Docetaxel

25. Advanced HER2-Positive Breast Cancer Future Directions

26. Abbreviations

27. Abbreviations (cont)

28. References

29. References (cont)

30. References (cont)

31. References (cont)

32. References (cont)

33. References (cont)

34. References (cont)

35. References (cont)