1. Nitrofurantoin's efficacy and safety as prophylaxis for urinary tract infections: a systematic review of the literature and meta-analysis of controlled trials 
A.E. Muller, E.M. Verhaegh, S. Harbarth, J.W. Mouton, A. Huttner 
Clinical Microbiology and Infection 
Volume 23, Issue 6, Pages (June 2017)
DOI: /j.cmi
Copyright © 2016 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

2. Fig. 1
Flow chart of the retrieval of studies evaluated in the meta-analysis of the efficacy of nitrofurantoin prophylaxis.
Clinical Microbiology and Infection  , DOI: ( /j.cmi )
Copyright © 2016 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

3. Fig. 2
Results of the meta-analysis for the prevention of urinary tract infection (UTI) when nitrofurantoin is compared with placebo/nothing. R, duration of prophylaxis; d, days; w, weeks; m, months; C-, comparator; F, female; M, male; O, duration of observation; A, adult; C, child.
Clinical Microbiology and Infection  , DOI: ( /j.cmi )
Copyright © 2016 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

4. Fig. 3
Results of the meta-analysis for the prevention of urinary tract infection (UTI) when nitrofurantoin is compared with other antibiotics for short-term prophylaxis. R, duration of prophylaxis; d, days; C-, comparator; F, female; M, male; O, duration of observation; TMP/SXT, trimethoprim/sulfamethoxazole; CFR, cefadroxil; CIP, ciprofloxacin.
Clinical Microbiology and Infection  , DOI: ( /j.cmi )
Copyright © 2016 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

5. Fig. 4
Results of the meta-analysis for the prevention of urinary tract infection (UTI) when nitrofurantoin is compared with other antibiotics used for long-term prophylaxis. R, duration of prophylaxis; d, days; C-, comparator; F, female; M, male; A, adult; C, child; PEN, penicillin; AMX, amoxicillin; PMC, pivmecillinam; CEC, cefaclor; CFX, cefixime; CIN, cinoxacin; NOR, norfloxacin; TMP/SXT, trimethoprim/sulfamethoxazole; TRM, trimethoprim; MH, methenamine hippurate; MM, methenamine mandelate; SMT, sulfamethizole; MAN, d-mannose.
Clinical Microbiology and Infection  , DOI: ( /j.cmi )
Copyright © 2016 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

6. Fig. 5
Results of the meta-analysis for (mild) adverse effects for long-term use of nitrofurantoin compared with other antibiotics. R, duration of prophylaxis; d, days; C-, comparator; F, female; M, male; A, adult; C, child; PEN, penicillin; AMX, amoxicillin; PMC, pivmecillinam; CEC, cefaclor; CFX, cefixime; CIN, cinoxacin; NOR, norfloxacin; TMP/SXT, trimethoprim/sulfamethoxazole; TRM, trimethoprim; MH, methenamine hippurate; MM, methenamine mandelate; SMT, sulfamethizole; MAN, d-mannose.
Clinical Microbiology and Infection  , DOI: ( /j.cmi )
Copyright © 2016 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions