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Carotid endarterectomy impairs blood pressure homeostasis by reducing the physiologic baroreflex reserve  S.A. Reza Nouraei, MA MBBChir, Pippa G. Al-Rawi,

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Presentation on theme: "Carotid endarterectomy impairs blood pressure homeostasis by reducing the physiologic baroreflex reserve  S.A. Reza Nouraei, MA MBBChir, Pippa G. Al-Rawi,"— Presentation transcript:

1 Carotid endarterectomy impairs blood pressure homeostasis by reducing the physiologic baroreflex reserve  S.A. Reza Nouraei, MA MBBChir, Pippa G. Al-Rawi, BSc, Dominique Sigaudo-Roussel, PhD, Dino A. Giussani, PhD, Michael E. Gaunt, MD(Dist)  Journal of Vascular Surgery  Volume 41, Issue 4, Pages (April 2005) DOI: /j.jvs Copyright © 2005 The Society for Vascular Surgery Terms and Conditions

2 Fig 1 The overall hemodynamic response to carotid endarterectomy in diseased (n = 23) and control (n = 37) groups. Results are mean ± SE. BP, Blood pressure; HR, heart rate. Results are mean ± SE. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2005 The Society for Vascular Surgery Terms and Conditions

3 Fig 2 Differential response blood pressure (BP) and heart rate of patients with normal (control, n = 37) and diseased (n = 23) contralateral carotid artery to carotid endarterectomy. Results are mean ± SE. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2005 The Society for Vascular Surgery Terms and Conditions

4 Fig 3 A, Intraluminal rub test before carotid endarterectomy led to a significant hypotensive response in patients with diseased contralateral carotid artery (n = 23) but not in patients with normal (control, n = 37) contralateral carotid. B, This response was obliterated after carotid endarterectomy. Results are mean ± SE. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2005 The Society for Vascular Surgery Terms and Conditions

5 Fig 4 A, Carotid endarterectomy led to a significant hypertensive resetting of the baroreflex operating set point, more significantly affecting patients with contralateral carotid artery disease. B, Peak spontaneous baroreflex sensitivity was significantly reduced in both groups after carotid endarterectomy, but the difference between the two groups did not reach statistical significance (diseased, n = 23; control, n = 37). Results are mean ± SE. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2005 The Society for Vascular Surgery Terms and Conditions

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