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Subjective Perception of Lactose Intolerance Does Not Always Indicate Lactose Malabsorption  Francesc Casellas, Anna Aparici, Maite Casaus, Purificación.

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Presentation on theme: "Subjective Perception of Lactose Intolerance Does Not Always Indicate Lactose Malabsorption  Francesc Casellas, Anna Aparici, Maite Casaus, Purificación."— Presentation transcript:

1 Subjective Perception of Lactose Intolerance Does Not Always Indicate Lactose Malabsorption 
Francesc Casellas, Anna Aparici, Maite Casaus, Purificación Rodríguez, Juan R. Malagelada  Clinical Gastroenterology and Hepatology  Volume 8, Issue 7, Pages (July 2010) DOI: /j.cgh Copyright © 2010 AGA Institute Terms and Conditions

2 Figure 1 Results of the home symptoms questionnaire (black columns) and the 50-g lactose challenge questionnaire (white columns). Results are expressed as medians and 25th–75th percentiles. All items in the questionnaire except vomiting were scored significantly more highly at home than after lactose challenge. *P < .01. Clinical Gastroenterology and Hepatology 2010 8, DOI: ( /j.cgh ) Copyright © 2010 AGA Institute Terms and Conditions

3 Figure 2 Results of the symptom questionnaire according to lactose absorption status as established by lactose HBT. Upper figure represents the results of each item and total score obtained in lactose absorbers, and lower figure represents these results in lactose malabsorbers. Results of home symptoms are represented in black columns and those recorded after 50-g lactose challenge in white columns. Results are expressed as medians and 25th–75th percentiles. Note that home symptoms are highly scored regardless of lactase status. *P < .01; #P < .05. Clinical Gastroenterology and Hepatology 2010 8, DOI: ( /j.cgh ) Copyright © 2010 AGA Institute Terms and Conditions

4 Figure 3 Results of the questionnaire according to lactose tolerance established by symptom response to 50-g lactose challenge. Upper figure represents the results of each questionnaire item and total score in lactose tolerants, and lower figure represents these results in lactose intolerants. Results of home symptoms are represented in black columns and those after 50-g lactose challenge in white columns. Results are expressed as medians and 25th–75th percentiles. Note that home symptoms were scored more highly by lactose tolerants. *P < .01; #P < .05. Clinical Gastroenterology and Hepatology 2010 8, DOI: ( /j.cgh ) Copyright © 2010 AGA Institute Terms and Conditions

5 Figure 4 Influence of gender on scoring of symptoms questionnaire. Men's results are represented in gray columns and women's results in white columns. Results are expressed as medians and 25th–75th percentiles. Home symptoms are scored more highly than symptoms after lactose challenge regardless of gender. *P < .05. Clinical Gastroenterology and Hepatology 2010 8, DOI: ( /j.cgh ) Copyright © 2010 AGA Institute Terms and Conditions


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