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Low-dose fluticasone propionate compared with montelukast for first-line treatment of persistent asthma: A randomized clinical trial  William Busse, MDa,

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Presentation on theme: "Low-dose fluticasone propionate compared with montelukast for first-line treatment of persistent asthma: A randomized clinical trial  William Busse, MDa,"— Presentation transcript:

1 Low-dose fluticasone propionate compared with montelukast for first-line treatment of persistent asthma: A randomized clinical trial  William Busse, MDa, Gordon D. Raphael, MDb, Stanley Galant, MDc, Chris Kalberg, PhDd, Stacey Goode-Sellers, BSd, Sharon Srebro, MDd, Lisa Edwards, PhDd, Kathy Rickard, MDd  Journal of Allergy and Clinical Immunology  Volume 107, Issue 3, Pages (March 2001) DOI: /mai Copyright © 2001 Mosby, Inc. Terms and Conditions

2 Fig. 1 Mean percent change from baseline in FEV1 in patients receiving FP or montelukast (MON) during the 24-week double-blind treatment period. *P < .001, FP versus montelukast. BL, Baseline; EP, endpoint. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2001 Mosby, Inc. Terms and Conditions

3 Fig. 2 Mean change from baseline in morning PEF in patients receiving FP or montelukast (MON) during the 24-week double-blind treatment period. *P < .001, FP versus montelukast. BL, Baseline; EP, endpoint. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2001 Mosby, Inc. Terms and Conditions

4 Fig. 3 Mean change from baseline in morning PEF stratified by baseline percent predicted FEV1. *P ≤ .007, FP versus montelukast (MON) at endpoint. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2001 Mosby, Inc. Terms and Conditions

5 Fig. 4 Percentages of patients who rated their overall satisfaction with FP or montelukast (MON) as satisfied, neutral, or dissatisfied. Satisfied includes patients who were slightly satisfied, satisfied, or very satisfied with treatment; Dissatisfied includes patients who were slightly dissatisfied, dissatisfied, or very dissatisfied with treatment. P < .001, FP versus montelukast. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2001 Mosby, Inc. Terms and Conditions

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