1. Quantifying Pulsus Paradoxus
Kara Bliley
Gina Lee
Allison Powers
Advisor: Tina V. Hartert, M.D., M.P.H.

2. Background Pulse Oximeter Measures O2 saturation of hemoglobin
Normal value
How does it work?

3. Background
Pulsus Paradoxus
Definition
Phenomenas

4. Objective To develop an algorithm to quantify pulsus paradoxus
Normal arterial pressure trace:
Pulsus paradoxus:

5. Potential Applications
Continuous and real time monitoring of disease severity
Analyzing changes in intrathoracic pressure
Monitoring changes in work of breathing
Possible use for home studies of sleep disorders

6. Methods Pulse oximetry tracings scanned into computer
Matlab program developed to analyze tracings
Correlation of findings with clinical criteria

7. Methods Develop a standard measuring method Waveform analysis:
area under curve
height difference
Area under curve
Height difference

8. Acknowledgements
VUMC Intensive Care Unit Staff
Patrick Norris