1. Expression Diversity Adds Richness to T Cell Populations
Dean Franckaert, Adrian Liston 
Immunity 
Volume 45, Issue 5, Pages (November 2016)
DOI: /j.immuni
Copyright © 2016 Elsevier Inc. Terms and Conditions

2. Figure 1 Categories of Cell-to-Cell Expression Variation
Classical flow cytometry histograms present the frequency of cells as a function of the expression of a given marker. A simple expression pattern might consist of a population that is “negative” for the marker (population A) and a population that is “positive” (population B). The expression difference between cells in these two populations can be considered discrete variation. Even within a single population, cell-to-cell expression variation exists (continuous variation), with some cells sitting above or below the median expression value of the population. A third layer of variability is added when multiple individuals are assessed, where the expression pattern of a single population (e.g., population B) is altered between individuals, either in terms of median expression or in terms of the variance from the median.
Immunity  , DOI: ( /j.immuni )
Copyright © 2016 Elsevier Inc. Terms and Conditions