1. Genomic risk of hepatitis C-related hepatocellular carcinoma
Yujin Hoshida, Bryan C. Fuchs, Kenneth K. Tanabe 
Journal of Hepatology 
Volume 56, Issue 3, Pages (March 2012)
DOI: /j.jhep
Copyright © 2011 European Association for the Study of the Liver Terms and Conditions

2. Fig. 1
Progression of chronic hepatitis C. After the establishment of chronic infection of hepatitis C virus, a subset of patients progresses into the next disease state assumedly through the interaction of host genetic, viral, and/or environmental risk factors. Risk allele A at rs is not associated with susceptibility to hepatitis C infection but is associated with occurrence of HCC. It remains to be determined exactly how risk allele A increases the risk of HCC development; for example by inducing chronic active hepatitis, cirrhosis progression, or tumor formation.
Journal of Hepatology  , DOI: ( /j.jhep )
Copyright © 2011 European Association for the Study of the Liver Terms and Conditions