1. The Cell Cycle
All phases except mitosis and cytokinesis are considered part of Interphase

2. Interphase
A cell spends most of its lifetime in interphase growing and replicating chromosomes.
Interphase is divided into:
G1 phase
S phase
G2 phase

3. Interphase: G1 phase
During the G1, or growth 1 phase of interphase, the cell makes new molecules and grows larger.
This phase can be long or short depending on the type of cell and the health of an organism.

4. Interphase: S phase S is for synthesis of more DNA.
During the S phase the uncoiled chromosomes, called chromatin, are replicated or duplicated.
During interphase, the nucleus looks like a dark blob (individual chromosomes are not visible).

5. Interphase: G2 phase
During the G2 or growth 2 phase the cell again synthesizes more molecules and grows larger.

6. The Chromosome
During interphase, the chromosomes exist as chromatin (stringy mass)
Each chromosome is duplicated during the S-phase of interphase
The original chromosome is attached with a centromere to its sister chromatid

8. Cell Division

9. Mitosis Review
SBI3U

11. Prophase Chromosomes become visible as they shorten and thicken
In animal cells, structures called centrioles move to opposite ends of the cell and provide attachment for spindle fibres
Nuclear membrane begins to disappear.

13. Metaphase
Sister chromatids move toward the equatorial plate by spindle fibers to form a metaphase plate
Spindle fibers are attached to centromeres

15. Anaphase
Centromeres divide and the chromatids are pulled by spindle fibers to opposite poles

17. Telophase Chromosomes lengthen Spindle fibres dissolve
Nuclear membrane forms around each set of chromatin
Followed by cytokinesis (division of cytoplasm)

18. Cytokinesis After mitosis, the cell divides all the cytoplasm and organelles in the process of cytokinesis.
In animal cells
Cleavage furrow develops, pinching off the cell into two
In plant cells
Cell plate forms into a new cell wall

19. Uncontrolled, rapid division of animal cells can be cancer.
If a cell ignores a signal to stop dividing, unchecked cell growth can result. Over time, the newly divided cells form a mass called a tumour.
A mutation (a permanent change in a cell’s DNA) is what causes the cells to ignore the “stop” signals. Cancer cells differ from normal cells in shape, size. and content.

20. Uncontrolled, rapid division of animal cells can be cancer.
Mutations can be inherited, can occur randomly, or can result from environmental factors such as exposure to ultraviolet light, radiation, or chemicals such as those found in cigarettes, alcohol, and other drugs.

21. Normal vs Cancerous Cell Division

22. Mitosis Rap

23. Mitosis Question Sheet
Complete Questions 1-9

24. Find onion cells in interphase!

25. Find cells undergoing prophase, metaphase, anaphase and telophase.