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The Prevalence and Diagnostic Utility of Endoscopic Features of Eosinophilic Esophagitis: A Meta-analysis  Hannah P. Kim, R. Brooks Vance, Nicholas J.

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Presentation on theme: "The Prevalence and Diagnostic Utility of Endoscopic Features of Eosinophilic Esophagitis: A Meta-analysis  Hannah P. Kim, R. Brooks Vance, Nicholas J."— Presentation transcript:

1 The Prevalence and Diagnostic Utility of Endoscopic Features of Eosinophilic Esophagitis: A Meta-analysis  Hannah P. Kim, R. Brooks Vance, Nicholas J. Shaheen, Evan S. Dellon  Clinical Gastroenterology and Hepatology  Volume 10, Issue 9, Pages e5 (September 2012) DOI: /j.cgh Copyright © 2012 AGA Institute Terms and Conditions

2 Figure 1 Flow diagram delineating the inclusion and exclusion of studies from the prevalence and operating characteristics analyses. Clinical Gastroenterology and Hepatology  , e5DOI: ( /j.cgh ) Copyright © 2012 AGA Institute Terms and Conditions

3 Figure 2 The effect of EoE prevalence on the PPV and NPV of esophageal rings for diagnosing EoE. The sensitivity and specificity of esophageal rings are held constant at 48% and 91%, respectively (these are the values calculated with a random-effects meta-analysis in this study). The prevalence of EoE is varied on the x-axis, and the resulting PPVs or NPVs are noted on the y-axis. Clinical Gastroenterology and Hepatology  , e5DOI: ( /j.cgh ) Copyright © 2012 AGA Institute Terms and Conditions

4 Figure 3 Typical endoscopic findings of EoE. (A) Prominent and fixed esophageal rings and narrow-caliber esophagus. (B) Subtle rings. (C) Rings and linear furrows, as well as mucosal pallor and decreased vasculature. (D) Linear furrows, mucosal pallor, and decreased vasculature. (E) Linear furrows and white plaques or exudates, as well as mucosal pallor and decreased vasculature. Clinical Gastroenterology and Hepatology  , e5DOI: ( /j.cgh ) Copyright © 2012 AGA Institute Terms and Conditions


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