1. Update on cystic fibrosis-related diabetes
Andrea Kelly, Antoinette Moran 
Journal of Cystic Fibrosis 
Volume 12, Issue 4, Pages (July 2013)
DOI: /j.jcf
Copyright © 2013 European Cystic Fibrosis Society. Terms and Conditions

2. Fig. 1
Incretin secretion and action. Glucose, fructose, free fatty acids, and to a lesser extent amino acids stimulate GLP-1 and GIP secretions. GLP-1 and GIP augment glucose stimulated insulin secretion and in animal models inhibit β-cell apoptosis and promote β-cell proliferation. GIP also promotes lipogenesis. GLP-1 suppresses glucagon secretion and delays gastric emptying.
Journal of Cystic Fibrosis  , DOI: ( /j.jcf )
Copyright © 2013 European Cystic Fibrosis Society. Terms and Conditions

3. Fig. 2
Plasma glucose and C-peptide in healthy controls (●), pancreatic sufficient CF (Ο), pancreatic insufficient CF without CFRD (▲), and CFRD (◊), adapted from Moran et al. [16].
Journal of Cystic Fibrosis  , DOI: ( /j.jcf )
Copyright © 2013 European Cystic Fibrosis Society. Terms and Conditions

4. Fig. 3
Enzyme replacement improves glucose excursion and increases GLP-1 and GIP secretion in CF. Plasma glucose (A), GLP-1 (B), and GIP (C) following a mixed meal tolerance test in healthy controls (▲), CF without enzymes (Ο) CF with enzymes (●), adapted from Kuo et al. [31].
Journal of Cystic Fibrosis  , DOI: ( /j.jcf )
Copyright © 2013 European Cystic Fibrosis Society. Terms and Conditions

5. Fig. 4
Mortality in CF subjects with and without CFRD, from Moran et al. [50]. Blue line: males, red line: females; solid line: CFRD; dashed line: CFRD.
Journal of Cystic Fibrosis  , DOI: ( /j.jcf )
Copyright © 2013 European Cystic Fibrosis Society. Terms and Conditions