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Common TLR5 Mutations Control Cancer Progression

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Presentation on theme: "Common TLR5 Mutations Control Cancer Progression"— Presentation transcript:

1 Common TLR5 Mutations Control Cancer Progression
Christina Pfirschke, Christopher Garris, Mikael J. Pittet  Cancer Cell  Volume 27, Issue 1, Pages 1-3 (January 2015) DOI: /j.ccell Copyright © 2015 Elsevier Inc. Terms and Conditions

2 Figure 1 Host-Microbiota Interactions Impact Tumor Immune Contexture
Tumor growth is sensitive to the inflammatory milieu. Sensing of commensal bacteria residing in the intestines elicits systemic cytokine responses that can be altered by mutation of TLR5 or through oral antibiotics. Changes in systemic cytokine levels can either promote or impair tumor growth depending upon the type of cancer involved. Cancer Cell  , 1-3DOI: ( /j.ccell ) Copyright © 2015 Elsevier Inc. Terms and Conditions

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