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Volume 20, Issue 6, Pages (June 2012)

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1 Volume 20, Issue 6, Pages 1280-1286 (June 2012)
Cellular Therapy With Ixmyelocel-T to Treat Critical Limb Ischemia: The Randomized, Double-blind, Placebo-controlled RESTORE-CLI Trial  Richard J Powell, William A Marston, Scott A Berceli, Raul Guzman, Timothy D Henry, Amy T Longcore, Theresa P Stern, Sharon Watling, Ronnda L Bartel  Molecular Therapy  Volume 20, Issue 6, Pages (June 2012) DOI: /mt Copyright © 2012 The American Society of Gene & Cell Therapy Terms and Conditions

2 Figure 1 Patient recruitment and disposition throughout the trial. N, number of patients. Molecular Therapy  , DOI: ( /mt ) Copyright © 2012 The American Society of Gene & Cell Therapy Terms and Conditions

3 Figure 2 Time to first occurrence of treatment failure for all patients injected. Kaplan–Meier survival plot of time to treatment failure (major amputation of injected leg, all-cause mortality, doubling of total wound surface area from baseline, de novo gangrene) for all patients injected. Censored observations are indicated by “+” symbols. CL, confidence limits; NA, not available. Molecular Therapy  , DOI: ( /mt ) Copyright © 2012 The American Society of Gene & Cell Therapy Terms and Conditions

4 Figure 3 Amputation-free survival for all patients injected. Kaplan–Meier survival plot of amputation-free survival (major amputation of injected leg or all-cause mortality) for all patients injected. Censored observations are indicated by “+” symbols. CL, confidence limits; NA, not available. Molecular Therapy  , DOI: ( /mt ) Copyright © 2012 The American Society of Gene & Cell Therapy Terms and Conditions

5 Figure 4 Time to first occurrence of treatment failure for all patients who had baseline wounds. Kaplan–Meier survival plot of time to treatment failure (major amputation of injected leg, all-cause mortality, doubling of total wound surface area from baseline, de novo gangrene) for post hoc analysis of patients who had baseline wounds. Censored observations are indicated by “+” symbols. CL, confidence limits; NA, not available. Molecular Therapy  , DOI: ( /mt ) Copyright © 2012 The American Society of Gene & Cell Therapy Terms and Conditions

6 Figure 5 Amputation-free survival for all patients who had baseline wounds. Kaplan–Meier survival plot of amputation-free survival (major amputation of injected leg or all-cause mortality) for post hoc analysis of patients who had baseline wounds. Censored observations are indicated by “+” symbols. CL, confidence limits; NA, not available. Molecular Therapy  , DOI: ( /mt ) Copyright © 2012 The American Society of Gene & Cell Therapy Terms and Conditions


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