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(Deoxyribonucleic Acid)
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DNA makes up the chromosomes of a cell.
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It is the blueprints for how to make all of the proteins in the organism
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Things that are made of proteins: skin, hair, blood, cells, and so on… (everything that you are made of!!)
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James Watson and Francis Crick were the scientists that discovered the actual structure of DNA
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They found that DNA is a double helix(a double spiral)
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DNA looks a little bit like a spiral staircase…
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Sugar phosphate Backbone
Nitrogen bases Sugar phosphate Backbone
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The handrails of DNA are made of sugar and phosphate
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The stairs of DNA are made of nitrogen bases.
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We say that DNA is composed of building blocks called NUCLEOTIDES.
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A nucleotide is made of:
a 5- carbon sugar (pentose)called deoxyribose a phosphate group a base (any one of four different kinds
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The phosphate bonds to the sugar, forming a “backbone” of sugars and phosphates.
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A base attaches to each sugar, so that the nucleotides form a chain.
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Adenine, Thymine, Cytosine, and Guanine
There are four bases: Adenine, Thymine, Cytosine, and Guanine
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Sugar phosphate Backbone
Adenine Guanine Thymine Cytosine Phosphate Sugar
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Adenine always bonds with Thymine
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Sugar phosphate Backbone
Adenine Thymine Phonsphate Sugar
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Guanine always bonds with Cytosine
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Sugar phosphate Backbone
Guanine Cytosine Phosphate Sugar
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Since DNA is a DOUBLE HELIX, it has two strands.
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The strands are COMPLEMENTARY to each other (the complement of each base is directly across from it).
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You can figure out what the structure of the complementary strand of DNA will be if you are given the original strand.
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Find the complementary strands base order:
Original strand: AATGCCGTTAATCGAT
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Answer: The complementary strand (underneath the original) would be:
AATGCCGTTAATCGAT TTACGGCAATTAGCTA (New Strand)
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DNA is copied in a process called replication
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When a mistake is made during replication, it is called a mutation
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Mutations can be very helpful, harmful, or have no effect on an organism
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Proteins are made of amino acids.
Proteins may be made of hundreds or thousands of amino acids.
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The section of DNA on a chromosome that directs the making of a specific protein is called a gene.
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Genes control proteins that build cells and tissues.
The gene gives directions for the order in which amino acids will be arranged.
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Remember proteins are made on ribosomes in the cytoplasm of a cell?
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The codes for making proteins are carried from the nucleus to the ribosomes by RNA.
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RNA is made up of only one strand.
RNA contains a nitrogen base called uracil (U) instead of thymine (T) and the sugar ribose (instead of deoxyribose).
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There are two kinds of RNA: transfer RNA (tRNA) and messenger RNA (mRNA).
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Protein assembly begins as mRNA moves out of the nucleus and attaches to the ribosomes.
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Pieces of tRNA pick up amino acids in the cytoplasm and bring them to the ribosomes.
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tRNA temporarily matches with mRNA and the amino acids become arranged according to the code.
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THE END!!
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Sugar phosphate Backbone
Nitrogen bases
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