1. Chris Hentschel, CEO MMV
APPMG Meeting. 11 June 2008
Chris Hentschel, CEO MMV
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2. An inconvenient truth Q: What Tools do we have to Conquer Malaria?
A: Tools are not enough!

3. The Six Step Global Malaria Business Plan
3 R&D Steps Control Steps
Learn &
Improve
Strategies
Discover
Develop
Deliver
Such an inspirational vision is fine ….. There have been many such before
This vision is however being backed by a GMBP under the auspices of the RBM partnership.
There is also separate “R&D for Eradication” process underway spearheaded by thr Bill and Melinda Gates Foundation. A key challenge will be to integrate the the now

4. Malaria eradication requires that the basic reproductive number, R0 < 1.
Drugs
& Diag
-nostics
Vaccines
IRS
ITNs
“R0 < 1 then eradication will follow, whereas if
R0 > 1 then the disease remains endemic.”

5. Values of R0 of well-known infectious diseases
Malaria
Measles Airborne
Pertussis Airborne droplet
Diphtheria Saliva
Smallpox Social contact
Polio Fecal-oral route 5-7
Rubella Airborne droplet
Mumps Airborne droplet
HIV/AIDS Sexual contact
SARS Airborne droplet
Influenza Airborne droplet

6. Evolution can enable re-emergence

7. Better Tools and Strategies
Eradication – a vision that now rests on four pillars
Better Tools and Strategies
Rapid Scale Up (SUFI)
Political Will
Economic
Growth
In Oct 2007 at the BMGF Malaria Forum the Foundations leadership backed by WHO and the leadership of the RBM partnership called for Eradication to be the fundamental goal of the efforts of all involved in the fight against malaria.
MMV had in fact preempted such global leadership its Annual report published in May 2007….
Malaria Elimination
and Eradication

8. Indian Eradication Poster ca 1960

9. Thank You
Never doubt that a small, group of thoughtful, committed citizens can change the world. Indeed, it is the only thing that ever has.                                    
Margaret Mead

10. Thank You
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