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Dynamics of Fat Absorption and Effect of Sham Feeding on Postprandial Lipema
Rosa N. Chavez–Jauregui, Richard D. Mattes, Elizabeth J. Parks Gastroenterology Volume 139, Issue 5, Pages (November 2010) DOI: /j.gastro Copyright © 2010 AGA Institute Terms and Conditions
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Figure 1 Inpatient study time line. See Materials and Methods for specifics of protocol. CHO, carbohydrate; CRC, clinical research center; IV, intravenous; TE, total energy. Gastroenterology , DOI: ( /j.gastro ) Copyright © 2010 AGA Institute Terms and Conditions
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Figure 2 Serum concentrations of glucose, insulin, and NEFAs. See Materials and Methods for specifics of protocol. HF sensory exposure denoted with filled symbols; LF sensory exposure, unfilled symbols. Time points that are significantly different (P < .05) are denoted by asterisks. Gastroenterology , DOI: ( /j.gastro ) Copyright © 2010 AGA Institute Terms and Conditions
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Figure 3 Concentrations of serum TAGs and TAGs in lipoprotein fractions Sf >400 and Sf 60–400. See legend of Figure 2 for details. Gastroenterology , DOI: ( /j.gastro ) Copyright © 2010 AGA Institute Terms and Conditions
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Figure 4 Sf >400 lipoprotein TAG FA labeling (A) and accounting of the sources of lipoprotein TAG oleic acid by labeling 2 consecutive meals (B). (A) The evening meal fed the night before was labeled with 13C2 triolein, and the morning capsules were labeled with 13C7 triolein. (B) Sources of the total day-long iAUC of Sf >400 TAG oleic acid were identified from labeling patterns and enrichments of the Evmeal (hatched area), capsules (filled gray area), and the sum minus these 2 sources. Gastroenterology , DOI: ( /j.gastro ) Copyright © 2010 AGA Institute Terms and Conditions
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Figure 5 Pattern of labeling of lipoproteins Sf >400 TAGs. Evening meal label data (solid line) and capsule label data (dashed lines) are presented for individual subjects from HF and LF sensory exposure. The unit on the y-axis represents the percentage of Sf >400 lipoprotein TAG oleic acid that is labeled. Horizontal arrows highlight similar starting enrichment of 13C2 at the beginning of the experiment, asterisks denote cephalic-phase peaks, and upward arrows highlight acute increases in the use of the 13C2 label at the onset of lunch, 4.75 hours. Gastroenterology , DOI: ( /j.gastro ) Copyright © 2010 AGA Institute Terms and Conditions
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Figure 6 Relationships between subject body fat residual Evmeal label, subject percentage of body fat, and residual label and peak capsule enrichments. Data are from the HF (filled symbols, solid regression line) and the LF experiments (unfilled symbols, dashed line). (A) Relationship between the residual Evmeal enrichment in Sf >400 TAGs in the fasting state during HF and LF sensory tests. (B) Subject body fat and the residual Evmeal label in Sf >400 TAGs in the fasting state. (C) Fasting enrichment of Evmeal label in the morning vs capsule label enrichment during HF sensory exposure and (D) during LF sensory exposure. Gastroenterology , DOI: ( /j.gastro ) Copyright © 2010 AGA Institute Terms and Conditions
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