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Total Liquid Ventilation Reduces Lung Injury in Piglets After Cardiopulmonary Bypass  Lijun Jiang, MD, Qiang Wang, MD, Yinglong Liu, MD, Ming Du, MD, Xiangdong.

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Presentation on theme: "Total Liquid Ventilation Reduces Lung Injury in Piglets After Cardiopulmonary Bypass  Lijun Jiang, MD, Qiang Wang, MD, Yinglong Liu, MD, Ming Du, MD, Xiangdong."— Presentation transcript:

1 Total Liquid Ventilation Reduces Lung Injury in Piglets After Cardiopulmonary Bypass 
Lijun Jiang, MD, Qiang Wang, MD, Yinglong Liu, MD, Ming Du, MD, Xiangdong Shen, MD, Xiaogang Guo, MD, Song Wu, MD  The Annals of Thoracic Surgery  Volume 82, Issue 1, Pages (July 2006) DOI: /j.athoracsur Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 BAL concentrations of interleukin-6 (pg/mL), interleukin-8 (pg/mL) and myeloperoxidase (MPO) (u/L) at the end of the observation period. Results are presented as mean and SD. There was a significant difference in the interleukin-6 and MPO levels between groups. (*p< 0.05; †p< by one way analysis of variance; black bar = control; grey bar = total liquid ventilation.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Plasma concentrations of interleukin-6 (pg/mL), interleukin-8 (pg/mL), and myeloperoxidase (MPO) (u/L) at the end of the observation period. Results are presented as mean and SD. There was no significant difference in the interleukin-6, interleukin-8, and MPO levels between groups. (Black bar = control; grey bar = total liquid ventilation.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Representative lung section indicates an unimpaired lung tissue from a normal animal that did not receive cardiopulmonary bypass (hematoxylin and eosin, ×200). The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

5 Fig 4 Representative lung section from an animal treated with conventional gas ventilation after cardiopulmonary bypass indicates significant lung injury (hematoxylin and eosin, ×200). The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

6 Fig 5 Representative lung section from an animal treated with total liquid ventilation after cardiopulmonary bypass indicates significantly reduced lung injury (hematoxylin and eosin, ×200). The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

7 Fig 6 Inflammation score and total lung injury score. Results are presented as mean and SD. There was a significant difference in the inflammation score and total lung injury score between groups. (*p < 0.05; black bar = control; grey bar = total liquid ventilation.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

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