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Figure 4 Abundance of cytokines which showed significant difference in expression in the plasma and the cultured PBMC of patients with RRMS Abundance of.

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Presentation on theme: "Figure 4 Abundance of cytokines which showed significant difference in expression in the plasma and the cultured PBMC of patients with RRMS Abundance of."— Presentation transcript:

1 Figure 4 Abundance of cytokines which showed significant difference in expression in the plasma and the cultured PBMC of patients with RRMS Abundance of cytokines which showed significant difference in expression in the plasma and the cultured PBMC of patients with RRMS Multiplex cytokine assay analysis of plasma levels of (A) TNFβ and (B) CCL17. Multiplex cytokine assay analysis was also performed on unactivated PBMC supernatant levels of (C) IFN-γ, (D) IL-2, (E) IL-4, (F) IL-6, (G) IL-12, and (H) IL-1β for NT (n = 3), DMF-treated patients with no lymphopenia (DMF-N, n = 3 for plasma and n = 4 for supernatants), and DMF-treated patients who developed lymphopenia (DMF-L, n = 3 for plasma and n = 4 for supernatants). The horizontal lines indicate the average mean of each group, and the bars are the SEM. p Values are indicated as insets; those reaching statistical significance are highlighted in red. DMF = dimethyl fumarate; FTY = fingolimod; IFN = interferon; IL = interleukin; NT = untreated; PBMC = peripheral blood mononuclear cell; RRMS = relapsing-remitting MS. Maryam Nakhaei-Nejad et al. Neurol Neuroimmunol Neuroinflamm 2018;5:e432 Copyright © 2017 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology.

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Figure e-1A.
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