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Outcome and Minimal Residual Disease Monitoring in Patients with t(16;21) Acute Myelogenous Leukemia Undergoing Allogeneic Hematopoietic Stem Cell Transplantation 

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Presentation on theme: "Outcome and Minimal Residual Disease Monitoring in Patients with t(16;21) Acute Myelogenous Leukemia Undergoing Allogeneic Hematopoietic Stem Cell Transplantation "— Presentation transcript:

1 Outcome and Minimal Residual Disease Monitoring in Patients with t(16;21) Acute Myelogenous Leukemia Undergoing Allogeneic Hematopoietic Stem Cell Transplantation  Ya-Zhen Qin, Yao Chen, Lan-Ping Xu, Yu Wang, Xiao-Hui Zhang, Huan Chen, Xiao-Su Zhao, Kai-Yan Liu, Xiao-Jun Huang  Biology of Blood and Marrow Transplantation  Volume 24, Issue 1, Pages (January 2018) DOI: /j.bbmt Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 CIR (A), DFS (B), and OS (C) for the whole cohort.
Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

3 Figure 2 Sequential TLS-ERG transcript levels at diagnosis, pre-HSCT, and post-HSCT in 14 patients. The number in the boxes represent TLS-ERG transcript levels at diagnosis. Arrows represent interventions; 8 patients received preemptive DLI, and 1 patient received IFN-α. Dx, at diagnosis; UKN, unknown; HR, hematologic relapse; EMR, extramedullary relapse; NRM, nonrelapse mortality. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

4 Figure 3 Dynamics of TLS-ERG transcript levels after treatment with modified DLI (7 patients; solid line) or IFN-α (1 patient; dashed line). Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions


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