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A Randomized Controlled Trial of Enemas in Combination With Oral Laxative Therapy for Children With Chronic Constipation  Marloes E.J. Bongers, Maartje.

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Presentation on theme: "A Randomized Controlled Trial of Enemas in Combination With Oral Laxative Therapy for Children With Chronic Constipation  Marloes E.J. Bongers, Maartje."— Presentation transcript:

1 A Randomized Controlled Trial of Enemas in Combination With Oral Laxative Therapy for Children With Chronic Constipation  Marloes E.J. Bongers, Maartje M. van den Berg, Johannes B. Reitsma, Wieger P. Voskuijl, Marc A. Benninga  Clinical Gastroenterology and Hepatology  Volume 7, Issue 10, Pages (October 2009) DOI: /j.cgh Copyright © 2009 AGA Institute Terms and Conditions

2 Figure 1 Defecation frequency per week for both treatment groups. *Overall test for differences between IG and CG at all 4 time points; results depicted are modeled means by using a linear mixed model. Additional tests for differences between IG and CG at specific time points: #P = .63; §P = .02; ¥P = .46; $P = .02. (Dotted line indicates the lower limit of a normal defecation frequency per week.) Clinical Gastroenterology and Hepatology 2009 7, DOI: ( /j.cgh ) Copyright © 2009 AGA Institute Terms and Conditions

3 Figure 2 Fecal incontinence frequency <1/week for both treatment groups. *Overall test for differences between IG and CG at all 4 time points by using GEE analysis. Clinical Gastroenterology and Hepatology 2009 7, DOI: ( /j.cgh ) Copyright © 2009 AGA Institute Terms and Conditions

4 Figure 3 Overall success for both treatment groups. *Overall test for differences between IG and CG at all 4 time points by using GEE analysis. Clinical Gastroenterology and Hepatology 2009 7, DOI: ( /j.cgh ) Copyright © 2009 AGA Institute Terms and Conditions


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