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William G. Kaelin, Peter J. Ratcliffe  Molecular Cell 

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1 Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway 
William G. Kaelin, Peter J. Ratcliffe  Molecular Cell  Volume 30, Issue 4, Pages (May 2008) DOI: /j.molcel Copyright © 2008 Elsevier Inc. Terms and Conditions

2 Figure 1 Central Role of PHD Prolyl Hydroxylases and the HIF Transcription Factor in Response to Hypoxia See text for details. Stimulatory interactions are indicated with ↓. Inhibitory interactions are indicated with ⊥. Molecular Cell  , DOI: ( /j.molcel ) Copyright © 2008 Elsevier Inc. Terms and Conditions

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