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Pooled Systemic Efficacy and Safety Data from the Pivotal Phase II Studies (NP28673 and NP28761) of Alectinib in ALK-positive Non-Small Cell Lung Cancer 

Published byShyama Chakrabarti Modified over 6 years ago

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Presentation on theme: "Pooled Systemic Efficacy and Safety Data from the Pivotal Phase II Studies (NP28673 and NP28761) of Alectinib in ALK-positive Non-Small Cell Lung Cancer "— Presentation transcript:

1 Pooled Systemic Efficacy and Safety Data from the Pivotal Phase II Studies (NP and NP28761) of Alectinib in ALK-positive Non-Small Cell Lung Cancer  James Chih-Hsin Yang, MD, PhD, Sai-Hong Ignatius Ou, MD, PhD, Luigi De Petris, MD, Shirish Gadgeel, MD, Leena Gandhi, MD, PhD, Dong-Wan Kim, MD, PhD, Fabrice Barlesi, MD, PhD, Ramaswamy Govindan, MD, Anne-Marie C. Dingemans, MD, PhD, Lucio Crino, MD, Herve Lena, MD, Sanjay Popat, PhD, Jin Seok Ahn, MD, Eric Dansin, MD, Sophie Golding, MSc, Walter Bordogna, PhD, Bogdana Balas, MD, Peter N. Morcos, PharmD, Ali Zeaiter, MD, Alice T. Shaw, PhD  Journal of Thoracic Oncology  Volume 12, Issue 10, Pages (October 2017) DOI: /j.jtho Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

2 Figure 1 Independent review committee–assessed progression-free survival of the pooled population (intent-to-treat population [N = 225]). Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

3 Figure 2 Overall survival of the pooled population (intent-to-treat population [N = 225]). Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

4 Supplementary Figure 1 CONSORT diagram
∗IRC RE population defined as patients with measurable disease at baseline according to the IRC. (Not possible to include information regarding the reason for treatment discontinuations in either study, as these data are not availble). Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

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