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Improved Overall Survival with Aggressive Primary Tumor Radiotherapy for Patients with Metastatic Esophageal Cancer  David M. Guttmann, MD, MTR, Nandita.

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Presentation on theme: "Improved Overall Survival with Aggressive Primary Tumor Radiotherapy for Patients with Metastatic Esophageal Cancer  David M. Guttmann, MD, MTR, Nandita."— Presentation transcript:

1 Improved Overall Survival with Aggressive Primary Tumor Radiotherapy for Patients with Metastatic Esophageal Cancer  David M. Guttmann, MD, MTR, Nandita Mitra, PhD, Justin Bekelman, MD, James M. Metz, MD, John Plastaras, MD, PhD, Weiwei Feng, MS, Samuel Swisher-McClure, MD, MSHP  Journal of Thoracic Oncology  Volume 12, Issue 7, Pages (July 2017) DOI: /j.jtho Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

2 Figure 1 Temporal trends in use of chemotherapy alone and chemotherapy with low- or high-dose radiotherapy in metastatic esophageal cancer. The Spearman test for trend was significant for the trend of increasing utilization of chemotherapy alone over time (p trend < 0.001). Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

3 Figure 2 Inverse probability of treatment weighting adjusted overall survival in patients with metastatic esophageal cancer treated with chemotherapy alone (no radiotherapy [RT]), radiation doses less than 5040 cGy, or radiation doses of 5040 cGy or higher. The shaded region surrounding each line represents the upper and lower bounds of the 95% confidence interval. For the comparison, the hazard ratio is 0.72 (95% confidence interval: 0.70–0.74, p ≤ 0.001). Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions


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