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The Lancet Diabetes & Endocrinology
Cushing's conundrum: an unusual case of primary pigmented nodular adrenal disease in a 60-year-old woman Dr Jasna Aleksova, MBBS, Glenn Ward, Kim Taubman, FRACP, Jason Tan, FRACS, Stephen Farrell, FRACS, Stuart Galloway, FRACPA, Prof Richard J MacIsaac, FRACP, Nirupa Sachithanandan, FRACP The Lancet Diabetes & Endocrinology Volume 4, Issue 7, (July 2016) DOI: /S (15) Copyright © 2016 Elsevier Ltd Terms and Conditions
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Figure Imaging and histopathological findings
(A) Adrenal CT scan: the arrow shows an 8 mm nodule at the left inferior pole (Hounsefield units <5). (B) Iodocholesterol scan: bilateral uptake of norcholesterol, despite dexamethasone suppression and non-functioning left adrenal nodule. (C) Macroscopic appearance: bulky adrenals, with multiple pigmented nodules of less than 1 cm. (D) Microscopic appearance: normal cortex (x) and adjacent pigmented nodule (y), with presence of melanin staining within the cytoplasm of the nodule cells (×20 magnification). The Lancet Diabetes & Endocrinology 2016 4, DOI: ( /S (15) ) Copyright © 2016 Elsevier Ltd Terms and Conditions
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