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Volume 143, Issue 1, Pages 14-18 (January 2013)
Change in Sweat Chloride as a Clinical End Point in Cystic Fibrosis Clinical Trials Anthony G. Durmowicz, MD, Kimberly A. Witzmann, MD, Curtis J. Rosebraugh, MD, MPH, Badrul A. Chowdhury, MD, PhD CHEST Volume 143, Issue 1, Pages (January 2013) DOI: /chest Copyright © 2013 The American College of Chest Physicians Terms and Conditions
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Figure 1 Scatter plots of absolute change from baseline in % predicted FEV1 vs absolute change from baseline in sweat chloride at wk 24 in patients treated with ivacaftor for trial 1 (adolescent/adult) and trial 2 (children). (Adapted from Center for Drug Evaluation and Research.9) CHEST , 14-18DOI: ( /chest ) Copyright © 2013 The American College of Chest Physicians Terms and Conditions
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