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Colchicine lack of effectiveness in symptom and inflammation modification in knee osteoarthritis (COLKOA): a randomized controlled trial  Y.Y. Leung,

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Presentation on theme: "Colchicine lack of effectiveness in symptom and inflammation modification in knee osteoarthritis (COLKOA): a randomized controlled trial  Y.Y. Leung,"— Presentation transcript:

1 Colchicine lack of effectiveness in symptom and inflammation modification in knee osteoarthritis (COLKOA): a randomized controlled trial  Y.Y. Leung, B. Haaland, J.L. Huebner, S.B.S. Wong, M. Tjai, C. Wang, B. Chowbay, J. Thumboo, B. Chakraborty, M.H. Tan, V.B. Kraus  Osteoarthritis and Cartilage  Volume 26, Issue 5, Pages (May 2018) DOI: /j.joca Copyright © 2018 The Author(s) Terms and Conditions

2 Fig. 1 Flow diagram for patient recruitment. knee OA (KOA) = KOA; APP = as-per-protocol; XR = radiography; KL = Kellgren and Lawrence grading system for radiography. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2018 The Author(s) Terms and Conditions

3 Fig. 2 Clinical Response of colchicine compared to placebo. ITT = intention-to-treat population; APP = as-per-protocol population; WOMAC = Western Ontario and McMaster Universities Osteoarthritis Index; OMERACT-OARSI = Response criteria by the Outcome Measures in Rheumatology Clinical Trials and Osteoarthritis Research Society International. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2018 The Author(s) Terms and Conditions


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