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Volume 90, Pages 8-12 (January 2019)

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Presentation on theme: "Volume 90, Pages 8-12 (January 2019)"— Presentation transcript:

1 Volume 90, Pages 8-12 (January 2019)
Hypothesis: Presymptomatic treatment of Sturge-Weber Syndrome With Aspirin and Antiepileptic Drugs May Delay Seizure Onset  Alyssa M. Day, BA, Adrienne M. Hammill, MD, PhD, Csaba Juhász, MD, PhD, Anna L. Pinto, MD, PhD, E. Steve Roach, MD, Charles E. McCulloch, PhD, Anne M. Comi, MD Karen L. Ball, BS, Brian J. Fisher, BBA, Jim I. Koenig, PhD, Michael T. Lawton, MD, Warren D. Lo, MD, Douglas A. Marchuk, PhD, Daniel K. Miles, MD, Marsha A. Moses, PhD, Angus A. Wilfong, MD Alyssa M. Day, BA, Adrienne M. Hammill, MD, PhD, Csaba Juhász, MD, PhD, Anna L. Pinto, MD, PhD, E. Steve Roach, MD, Charles E. McCulloch, PhD, Anne M. Comi, MD Karen L. Ball, BS, Brian J. Fisher, BBA, Jim I. Koenig, PhD, Michael T. Lawton, MD, Warren D. Lo, MD, Douglas A. Marchuk, PhD, Daniel K. Miles, MD, Marsha A. Moses, PhD, Angus A. Wilfong, MD  Pediatric Neurology  Volume 90, Pages 8-12 (January 2019) DOI: /j.pediatrneurol Copyright © Terms and Conditions

2 FIGURE 1 Process of participant selection using our SWS Center research database. SWS: Sturge-Weber syndrome Pediatric Neurology  , 8-12DOI: ( /j.pediatrneurol ) Copyright © Terms and Conditions

3 FIGURE 2 Medians of the neuroscores of presymptomatic treatment (aspirin only) versus postsymptomatic treatment. Graph of the medians and ranges of the neurological scores of those presymptomatically treated with aspirin only and postsymptomatically treated. *There were significant differences between the two groups (Wilcoxon-signed rank test). Pediatric Neurology  , 8-12DOI: ( /j.pediatrneurol ) Copyright © Terms and Conditions

4 FIGURE 3 Medians of the neuroscores of presymptomatic treatment (aspirin and anti-epileptic) versus postsymptomatic treatment. Graph of the medians and ranges of the neurological scores of those presymptomatically treated with both aspirin and antiepileptic drugs versus those postsymptomatically treated. *The seizure subscore is significantly lower for those given presymptomatic treatment (Wilcoxon-signed rank test, P < 0.05). Pediatric Neurology  , 8-12DOI: ( /j.pediatrneurol ) Copyright © Terms and Conditions


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