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Is desmoplasia a protective factor for survival in patients with colorectal carcinoma?  Alessandro Caporale, Anna Rita Vestri, Eugenio Benvenuto, Mauro.

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Presentation on theme: "Is desmoplasia a protective factor for survival in patients with colorectal carcinoma?  Alessandro Caporale, Anna Rita Vestri, Eugenio Benvenuto, Mauro."— Presentation transcript:

1 Is desmoplasia a protective factor for survival in patients with colorectal carcinoma? 
Alessandro Caporale, Anna Rita Vestri, Eugenio Benvenuto, Mauro Mariotti, Umile Michele Cosenza, Massimo Scarpini, Andrea Giuliani, Pietro Mingazzini, Francesco Angelico  Clinical Gastroenterology and Hepatology  Volume 3, Issue 4, Pages (April 2005) DOI: /S (04) Copyright © 2005 American Gastroenterological Association Terms and Conditions

2 Figure 1 Advancing edge of the tumor. Muscularis propria infiltration with absence of a desmoplastic reaction. Van Gieson 200×. Clinical Gastroenterology and Hepatology 2005 3, DOI: ( /S (04) ) Copyright © 2005 American Gastroenterological Association Terms and Conditions

3 Figure 2 Advancing edge of the tumor. Muscularis propria infiltration with presence of a desmoplastic reaction. Van Gieson 200×. Clinical Gastroenterology and Hepatology 2005 3, DOI: ( /S (04) ) Copyright © 2005 American Gastroenterological Association Terms and Conditions

4 Figure 3 Estimated proportion surviving according to presence or absence of desmoplasia in the group of patients with stage I colorectal adenocarcinoma (P = .001). Clinical Gastroenterology and Hepatology 2005 3, DOI: ( /S (04) ) Copyright © 2005 American Gastroenterological Association Terms and Conditions

5 Figure 4 Estimated proportion surviving according to presence or absence of desmoplasia in the group of patients with stage II colorectal adenocarcinoma (P < .0001). Clinical Gastroenterology and Hepatology 2005 3, DOI: ( /S (04) ) Copyright © 2005 American Gastroenterological Association Terms and Conditions

6 Figure 5 Estimated proportion surviving according to presence or absence of desmoplasia in the group of patients with stage III colorectal adenocarcinoma (P = .001). Clinical Gastroenterology and Hepatology 2005 3, DOI: ( /S (04) ) Copyright © 2005 American Gastroenterological Association Terms and Conditions

7 Figure 6 Estimated proportion surviving according to presence or absence of desmoplasia in the group of patients with stage IV colorectal adenocarcinoma (P = .6327). Clinical Gastroenterology and Hepatology 2005 3, DOI: ( /S (04) ) Copyright © 2005 American Gastroenterological Association Terms and Conditions


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