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Volume 142, Issue 6, Pages 1279-1287.e3 (May 2012)
Animal Models for the Study of Hepatitis C Virus Infection and Related Liver Disease Jens Bukh Gastroenterology Volume 142, Issue 6, Pages e3 (May 2012) DOI: /j.gastro Copyright © 2012 AGA Institute Terms and Conditions
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Figure 1 Proposed animal models in HCV research. For each indicated model, specific characteristics on utility and applications are indicated. For all small animal models there are areas of research that are not currently feasible, indicated with “not relevant.” aTested by intrahepatic transfection with RNA transcripts from full-length HCV clones. bActivates a cellular reporter permitting bioluminescence imaging. cChimpanzees are not necessarily good models of chronic liver disease and HCV-associated hepatocellular carcinoma. Gastroenterology , e3DOI: ( /j.gastro ) Copyright © 2012 AGA Institute Terms and Conditions
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Gastroenterology 2012 142, 1279-1287. e3DOI: (10. 1053/j. gastro. 2012
Copyright © 2012 AGA Institute Terms and Conditions
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