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Improvements achieved in an oocyte donation program over a 10-year period: sequential increase in implantation and pregnancy rates and decrease in high-order.

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Presentation on theme: "Improvements achieved in an oocyte donation program over a 10-year period: sequential increase in implantation and pregnancy rates and decrease in high-order."— Presentation transcript:

1 Improvements achieved in an oocyte donation program over a 10-year period: sequential increase in implantation and pregnancy rates and decrease in high-order multiple pregnancies  Erdal Budak, M.D., Nicolas Garrido, Ph.D., Sergio Reis Soares, M.D., Marco Antonio Barreto Melo, M.D., Marcos Meseguer, Ph.D., Antonio Pellicer, M.D., José Remohí, M.D.  Fertility and Sterility  Volume 88, Issue 2, Pages (August 2007) DOI: /j.fertnstert Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

2 FIGURE 1 Indications for oocyte donation (cycles with embryo transfer = 7,186). POF = premature ovarian failure, RIF = recurrent IVF failure, RM = recurrent miscarriage. Budak. Evolution of a large oocyte donation program over a 10-year period. Fertil Steril 2007. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

3 FIGURE 2 Trends in number of embryos replaced in oocyte donation cycles between 1995 and Significantly fewer number of embryos were replaced with each successive period. ET = embryo transfer. Budak. Evolution of a large oocyte donation program over a 10-year period. Fertil Steril 2007. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

4 FIGURE 3 Trends in different cycle outcome parameters in oocyte donation cycles between 1995 and 2005. Budak. Evolution of a large oocyte donation program over a 10-year period. Fertil Steril 2007. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

5 FIGURE 4 Cumulative PRs rates in relation to different age groups: similar cumulative PR curves were observed for different age groups (P<.05). Budak. Evolution of a large oocyte donation program over a 10-year period. Fertil Steril 2007. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

6 FIGURE 5 Cumulative PRs in relation to indication for oocyte donation.
Budak. Evolution of a large oocyte donation program over a 10-year period. Fertil Steril 2007. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

7 FIGURE 6 Cumulative PRs in relation to sperm origin. MF = male factor.
Budak. Evolution of a large oocyte donation program over a 10-year period. Fertil Steril 2007. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions


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