1. The effect of sequential addition of sildenafil to first-line epoprostenol on exercise capacity measured using 6-min walk distance (6MWD) in the PACES clinical trial (Pulmonary Arterial Hypertension Combination Study of Epoprostenol and Sildenafil). ▪: epop...
The effect of sequential addition of sildenafil to first-line epoprostenol on exercise capacity measured using 6-min walk distance (6MWD) in the PACES clinical trial (Pulmonary Arterial Hypertension Combination Study of Epoprostenol and Sildenafil). ▪: epoprostenol plus sildenafil; •: epoprostenol plus placebo. #: placebo-adjusted increase of 28.8 m, 95% CI 13.9–43.8; p< Reproduced from [22] with permission of the publisher.
N. Galiè et al. Eur Respir Rev 2009;18:
©2009 by European Respiratory Society