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Fat digestion modulates gastrointestinal sensations induced by gastric distention and duodenal lipid in humans  Christine Feinle, Thomas Rades, Bärbel.

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Presentation on theme: "Fat digestion modulates gastrointestinal sensations induced by gastric distention and duodenal lipid in humans  Christine Feinle, Thomas Rades, Bärbel."— Presentation transcript:

1 Fat digestion modulates gastrointestinal sensations induced by gastric distention and duodenal lipid in humans  Christine Feinle, Thomas Rades, Bärbel Otto, Michael Fried  Gastroenterology  Volume 120, Issue 5, Pages (April 2001) DOI: /gast Copyright © 2001 American Gastroenterological Association Terms and Conditions

2 Fig. 1 Gastric volume changes in response to intestinal infusions at MDP. Data are means ± SEM. Significant differences *from respective THL condition, §from MCT, and #from SPE; P < 0.05. Gastroenterology  , DOI: ( /gast ) Copyright © 2001 American Gastroenterological Association Terms and Conditions

3 Fig. 2 Scores for nausea, fullness, pressure/pain, hunger, and bloating during isobaric gastric distention and duodenal infusion of the fat emulsions. Data are means ± SEM. Significant differences *from respective THL condition, §from MCT, and #from SPE; P < 0.05. Gastroenterology  , DOI: ( /gast ) Copyright © 2001 American Gastroenterological Association Terms and Conditions

4 Fig. 3 Maximally tolerated pressures during gastric distention and duodenal infusion of LCT, LCT-THL, MCT, MCT-THL, or SPE. Data are means ± SEM. Significant differences *from respective THL conditions, §from MCT, and #from SPE; P < 0.05. Gastroenterology  , DOI: ( /gast ) Copyright © 2001 American Gastroenterological Association Terms and Conditions

5 Fig. 4 Plasma CCK responses to duodenal infusion of the fat emulsions and gastric distention. LCT-THL, LCT containing the lipase inhibitor THL; MCT-THL, MCT containing THL. Data are means ± SEM. *Significantly different from all other conditions, P < 0.05. Gastroenterology  , DOI: ( /gast ) Copyright © 2001 American Gastroenterological Association Terms and Conditions


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