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The glutathione-S-transferase mu 1 (GSTM1) null genotype and increased neutrophil response to low-level ozone (0.06 ppm)  Neil E. Alexis, PhD, John C.

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Presentation on theme: "The glutathione-S-transferase mu 1 (GSTM1) null genotype and increased neutrophil response to low-level ozone (0.06 ppm)  Neil E. Alexis, PhD, John C."— Presentation transcript:

1 The glutathione-S-transferase mu 1 (GSTM1) null genotype and increased neutrophil response to low-level ozone (0.06 ppm)  Neil E. Alexis, PhD, John C. Lay, PhD, DVM, Haibo Zhou, PhD, Chong S. Kim, PhD, Michelle L. Hernandez, MD, Howard Kehrl, MD, Milan J. Hazucha, MD, PhD, Robert B. Devlin, PhD, David Diaz-Sanchez, PhD, David B. Peden, MD  Journal of Allergy and Clinical Immunology  Volume 131, Issue 2, Pages (February 2013) DOI: /j.jaci Copyright © Terms and Conditions

2 Fig 1 Mean ± SEM cell-surface phenotype expression (mean fluorescence intensity [MFI]) in responders and nonresponders after CA (solid diamonds) and O3 (open circles) exposure on sputum macrophages (A-C) and monocytes (D-F). Responders, but not nonresponders, had significantly (P < .05) increased expression for all markers after O3 versus CA exposure. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © Terms and Conditions


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