1. ALK/EML4 Fusion Gene May Be Found in Pure Squamous Carcinoma of the Lung 
Anna Caliò, MD, Alessia Nottegar, MD, Eliana Gilioli, MD, Emilio Bria, MD, Sara Pilotto, MD, Umberto Peretti, MD, Stefania Kinspergher, MD, Francesca Simionato, MD, Serena Pedron, BaSc, Sakari Knuutila, MD, Giampaolo Tortora, MD, Albino Eccher, MD, Antonio Santo, MD, Luca Tondulli, MD, Giorgio Inghirami, MD, Fabrizio Tabbò, MD, Guido Martignoni, MD, Marco Chilosi, MD, Aldo Scarpa, MD, PhD, Matteo Brunelli, MD, PhD 
Journal of Thoracic Oncology 
Volume 9, Issue 5, Pages (May 2014)
DOI: /JTO
Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions

2. FIGURE 1
Histopathological and immunohistochemical findings. Squamous cell carcinoma (hematoxylin and eosin) biopsy (A) and surgical sample (B). All cases strongly express n-p63 (C) and cytokeratin 5/6 (D) and are negative for thyroid transcription factor 1 (E) and Napsin (F).
Journal of Thoracic Oncology 2014 9, DOI: ( /JTO )
Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions

3. FIGURE 2
Interphase FISH analysis. A break-apart dual-color ALK probes, where the green and red signals are split apart demonstrate the break of the ALK gene (A), and a dual-color assay FISH EML4 and ALK probes, where the dual-fusion of adjacent red and green signals demonstrate the EML4-ALK rearrangement (B). FISH, fluorescence in situ hybridization; ALK, anaplastic lymphoma kinase; EML4, echinoderm microtubule associated protein like 4.
Journal of Thoracic Oncology 2014 9, DOI: ( /JTO )
Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions