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XMCPDT Does Have Correct Type I Error Rates
Jie Ding, Shili Lin The American Journal of Human Genetics Volume 82, Issue 2, Pages (February 2008) DOI: /j.ajhg Copyright © 2008 The American Society of Human Genetics Terms and Conditions
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Figure 1 Comparisons of Type I Error Rates and Powers between X-APL and XMCPDT (A and B) Type I error and power, respectively, for the setting with three-children families with at least one affected. (C and D) Type I error and power, respectively, for the setting with OSUMS family structures. The horizontal dashed line in (A) and (C) marks the nominal level of type I error rate. A total of 12 models were considered: recessive models RA–RF and multiplicative models MA–MF.1 XMCPDTT and XMCPDTE are XMCPDT with true or estimated allele frequencies. The American Journal of Human Genetics , DOI: ( /j.ajhg ) Copyright © 2008 The American Society of Human Genetics Terms and Conditions
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