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Telomere Length and Recurrence Risk after Curative Resection in Patients with Early- Stage Non–Small-Cell Lung Cancer: A Prospective Cohort Study  Eric.

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Presentation on theme: "Telomere Length and Recurrence Risk after Curative Resection in Patients with Early- Stage Non–Small-Cell Lung Cancer: A Prospective Cohort Study  Eric."— Presentation transcript:

1 Telomere Length and Recurrence Risk after Curative Resection in Patients with Early- Stage Non–Small-Cell Lung Cancer: A Prospective Cohort Study  Eric S. Kim, MD, Yuanqing Ye, PhD, Ara A. Vaporciyan, MD, Jinliang Xing, MD, PhD, Maosheng Huang, MD, Jian Gu, PhD, Jack A. Roth, MD, Scott M. Lippman, MD, Xifeng Wu, MD, PhD  Journal of Thoracic Oncology  Volume 10, Issue 2, Pages (February 2015) DOI: /JTO Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 Association of telomere length with sex, histology, and recurrence. Women had longer RTL compared with men, and the patients with adenocarcinoma demonstrated longer RTL compared with those of other histologic types. Patients who developed recurrence had significantly longer mean RTL compared with those without recurrence. RTL, relative telomere length. Journal of Thoracic Oncology  , DOI: ( /JTO ) Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 A–C, Kaplan–Meier estimates of recurrence in NSCLC patients with long versus short RTL following curative resection. In women with adenocarcinoma (D), those with longer telomeres had significantly longer time to recurrence. NSCLC, non–small-cell lung cancer; RTL, relative telomere length. Journal of Thoracic Oncology  , DOI: ( /JTO ) Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions


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