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Video capsule endoscopy to prospectively assess small bowel injury with celecoxib, naproxen plus omeprazole, and placebo  Jay L. Goldstein, Glenn M. Eisen,

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Presentation on theme: "Video capsule endoscopy to prospectively assess small bowel injury with celecoxib, naproxen plus omeprazole, and placebo  Jay L. Goldstein, Glenn M. Eisen,"— Presentation transcript:

1 Video capsule endoscopy to prospectively assess small bowel injury with celecoxib, naproxen plus omeprazole, and placebo  Jay L. Goldstein, Glenn M. Eisen, Blair Lewis, Ian M. Gralnek, Steve Zlotnick, John G. Fort  Clinical Gastroenterology and Hepatology  Volume 3, Issue 2, Pages (February 2005) DOI: /S (04) Copyright © 2005 American Gastroenterological Association Terms and Conditions

2 Figure 1 Trial profile. Clinical Gastroenterology and Hepatology 2005 3, DOI: ( /S (04) ) Copyright © 2005 American Gastroenterological Association Terms and Conditions

3 Figure 2 Mucosal break without hemorrhage (category 2 lesion), as defined in Table 1. Note the loss of mucosal integrity with surrounding erythema. Clinical Gastroenterology and Hepatology 2005 3, DOI: ( /S (04) ) Copyright © 2005 American Gastroenterological Association Terms and Conditions

4 Figure 3 Distribution of mucosal breaks among subjects with at least 1 mucosal break. The mean number of mucosal breaks was greater in subjects treated with naproxen + omeprazole than in subjects treated with either celecoxib or placebo. Clinical Gastroenterology and Hepatology 2005 3, DOI: ( /S (04) ) Copyright © 2005 American Gastroenterological Association Terms and Conditions


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