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Comparison of KRAS Mutation Analysis and FISH for Detecting Pancreatobiliary Tract Cancer in Cytology Specimens Collected During Endoscopic Retrograde.

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Presentation on theme: "Comparison of KRAS Mutation Analysis and FISH for Detecting Pancreatobiliary Tract Cancer in Cytology Specimens Collected During Endoscopic Retrograde."— Presentation transcript:

1 Comparison of KRAS Mutation Analysis and FISH for Detecting Pancreatobiliary Tract Cancer in Cytology Specimens Collected During Endoscopic Retrograde Cholangiopancreatography  Benjamin R. Kipp, Emily G. Barr Fritcher, Amy C. Clayton, Gregory J. Gores, Lewis R. Roberts, Jun Zhang, Michael J. Levy, Kevin C. Halling  The Journal of Molecular Diagnostics  Volume 12, Issue 6, Pages (November 2010) DOI: /jmoldx Copyright © 2010 American Society for Investigative Pathology and Association for Molecular Pathology Terms and Conditions

2 Figure 1 Specimen-processing flowchart, illustrating how pancreatobiliary samples were processed for routine clinical testing and KRAS mutation analysis. The Journal of Molecular Diagnostics  , DOI: ( /jmoldx ) Copyright © 2010 American Society for Investigative Pathology and Association for Molecular Pathology Terms and Conditions

3 Figure 2 Representative examples of normal and abnormal FISH and KRAS testing results. The Journal of Molecular Diagnostics  , DOI: ( /jmoldx ) Copyright © 2010 American Society for Investigative Pathology and Association for Molecular Pathology Terms and Conditions

4 Figure 3 Frequency of specific KRAS mutations detected by qPCR.
The Journal of Molecular Diagnostics  , DOI: ( /jmoldx ) Copyright © 2010 American Society for Investigative Pathology and Association for Molecular Pathology Terms and Conditions


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