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George Berberian, MD, T. Alexander Quinn, MS, Santos E

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1 Load dependence of cardiac output in biventricular pacing: Left ventricular volume overload in pigs 
George Berberian, MD, T. Alexander Quinn, MS, Santos E. Cabreriza, MBA, Cara A. Garofalo, MD, Dulce M. Barrios, Alan D. Weinberg, MS, Henry M. Spotnitz, MD  The Journal of Thoracic and Cardiovascular Surgery  Volume 131, Issue 3, Pages (March 2006) DOI: /j.jtcvs Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

2 Figure 1 The effect of atrioventricular delay (AVD) on cardiac output in both control and left ventricular volume overload (LVVO) states. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

3 Figure 2 The effect of ventricular-ventricular delay on cardiac output in both control and left ventricular volume overload (LVVO) states. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

4 Figure 3 The effect of atrioventricular delay (AVD) on left ventricular–to–left atrial graft flow. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

5 Figure 4 The effect of ventricular-ventricular delay on left ventricular–to–left atrial graft flow. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

6 Figure 5 Indices of mechanical interventricular synchrony at ventricular-ventricular delays yielding the best and worst cardiac output (CO) measurements. APP expresses asynchrony based on the pressure during the complete cardiac cycle, whereas Tup is restricted to the contraction phase. Both indices are positive for earlier right ventricular than left ventricular pressure and are equal to 0 for mechanical synchrony. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

7 Figure 6 Septal-posterior wall motion delay analysis showing a highly significant difference between optimal and minimal ventricular-ventricular delay settings. Optimal ventricular-ventricular delay settings were uniformly associated with positive wall motion delays. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions


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