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Elder siblings enhance the effect of filaggrin mutations on childhood eczema: Results from the 2 birth cohort studies LISAplus and GINIplus  Claudia Cramer,

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Presentation on theme: "Elder siblings enhance the effect of filaggrin mutations on childhood eczema: Results from the 2 birth cohort studies LISAplus and GINIplus  Claudia Cramer,"— Presentation transcript:

1 Elder siblings enhance the effect of filaggrin mutations on childhood eczema: Results from the 2 birth cohort studies LISAplus and GINIplus  Claudia Cramer, MSc, Elke Link, Maike Horster, BSc, Sibylle Koletzko, MD, Carl-P. Bauer, MD, Dietrich Berdel, MD, Andrea von Berg, MD, Irina Lehmann, PhD, Olf Herbarth, PhD, Michael Borte, MD, Beate Schaaf, MD, Heidrun Behrendt, MD, Chih-Mei Chen, PhD, Stefanie Sausenthaler, PhD, Thomas Illig, PhD, H.-Erich Wichmann, MD, PhD, Joachim Heinrich, PhD, Ursula Krämer, PhD  Journal of Allergy and Clinical Immunology  Volume 125, Issue 6, Pages e5 (June 2010) DOI: /j.jaci Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 Participation in LISAplus and GINIplus cohorts.
Journal of Allergy and Clinical Immunology  , e5DOI: ( /j.jaci ) Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3 1-year prevalences of doctor-diagnosed eczema in children up to the age of 6 years stratified for FLG mutations and elder siblings. Children who attended day care centers in the first 2 years of life excluded.FLG mutation +/Elder siblings +FLG mutation +/Elder siblings −FLG mutation −/Elder siblings +FLG mutation −/Elder siblings − Journal of Allergy and Clinical Immunology  , e5DOI: ( /j.jaci ) Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions

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