1. Figure 2 Chromosomal region 15q11.2–q13
Figure 2 | Chromosomal region 15q11.2–q13. In this schematic overview, paternally expressed genes are drawn as blue ellipses, maternally expressed genes are drawn as red ellipses, and genes that are expressed from both parental alleles are drawn as black ellipses. Orientation of transcription is indicated by horizontal arrows. Class I and class II deletions are drawn as horizontal lines. AS-IC, Angelman syndrome imprinting centre; BP, breakpoint cluster region; CH3, methylation; PWS-IC, Prader–Willi syndrome imprinting centre; snoRNA, small nucleolar RNA; SNRPN, small nuclear ribonucleoprotein-associated protein N; UBE3A, ubiquitin–protein ligase E3A.
Buiting, K. et al. (2016) Angelman syndrome — insights into a rare neurogenetic disorder
Nat. Rev. Neurol. doi: /nrneurol