1. A B D C Total adiponectin (μg/ml ) Hb ( g / dl ) r = -0.349 p = 0.00310 20 30 40 7 8 9 11 12 13 14
Total adiponectin (μg/ml )
Hb ( g / dl )
r =
p = 0.003 10 20 30 40 1
1.5 2
2.5 3
3.5
Total adiponectin (μg/ml )
log BNP ( pg / ml )
r = 0.440
p < 0.001 A B 10 20 30 1
1.5 2
2.5 3
3.5
log BNP ( pg / ml )
HMW adiponectin (μg/ml )
r = 0.400
p = 0.001 C 10 20 30 7 8 9 11 12 13 14
Hb ( g / dl )
HMW adiponectin (μg/ml )
r =
p = 0.007 D

2. Systolic blood pressure, mmHg 149.7 ± 19.6 149.5 ± 18.0 150.0 ± 20.6
Table 1.Demographic and clinical characteristics of the study population
total
male
female
p value
Number 70 30 40
Age, years
65.2 ± 8.6
65.7 ± 8.6
64.5 ± 8.7
0.682
duration of HD, months
67.5 (30.0, 132.0)
55.5 (29.5, 121.5)
81.0 (43.5, 148.5)
0.250
BMI, kg/ ㎡
20.4 ± 2.6
21.0 ± 2.0
19.9 ± 3.0
0.068
Systolic blood pressure, mmHg
149.7 ± 19.6
149.5 ± 18.0
150.0 ± 20.6
0.956
Diastolic blood pressure, mmHg
73.9 ± 9.4
75.8 ± 9.3
72.4 ± 9.2
0.134
Total cholesterol, mg/dl
168.5 ± 32.4
150.0 ± 25.9
182.4 ± 29.3
< 0.001
Triglycerides, mg/dl
93.5 (74.0, 119.8)
96.5 (73.0, 132.8)
91.0 (72.5, 116.8)
0.687
HDL cholesterol, mg/dl
45.0 ± 15.5
38.3 ± 12.6
50.1 ± 15.3
0.001
LDL cholesterol, mg/dl
97.5 ± 26.4
86.6 ± 22.7
105.1 ± 25.7
0.002
Albumin, g/dl
3.9 ± 0.4
0.895
Hemoglobin, g/dl
10.4 ± 1.0
0.406
HOMA-IR
1.48 (0.99, 1.87)
1.46 (1.00, 2.00)
1.48 (0.98, 1.85)
0.934
High-sensitive CRP, mg/dl
0.94 (0.35, 3.27 )
1.60 (0.40, 4.17)
0.63 (0.32, 1.40 )
0.050
BNP, pg/ml
258.6 (88.3, 306.8)
118.8 (75.4, 260.3)
224.1 (90.7, 356.1)
0.240
EF, %
67.7 ± 7.9
66.1 ± 9.8
68.9 ± 6.0
0.163
LVMI, g/
122.1 ± 34.7
122.8 ± 37.9
121.7 ± 32.5
0.899
Total adiponectin, ?g/mL
14.4 ± 7.0
10.5 ± 5.0
16.8 ± 7.1
HMW adiponectin, ?g/ml
8.4 ± 5.4
5.1 ± 3.2
10.5 ± 5.6
HMW/Total adiponectin ratio
0.53 ± 0.12
0.45 ± 0.10
0.59 ± 0.10
DM (n; %)
18 (25.7)
10 (33.3)
8 (19.0) NS
ACEIs/ARBs therapy (n; %)
16 (22.9)
7 (23.3)
9 (21.4)
Data are shown as mean ± SD or median (range). BMI = body mass indexes; HOMA-IR = homeostasis model assessment of insulin resistance; hsCRP = high sensitive C-reactive protein; BNP = B-type natriuretic peptide; EF = ejection fraction; LVMI = left ventricular mass index; HMW = high molecular weight; ACEIs/ARBs = angiotensin converting enzyme inhibitors/ angiotensin II receptor blockers

3. BMI = body mass indexes; HOMA-IR = homeostasis model assessment of insulin resistance; hsCRP = high sensitive
C-reactive protein; BNP = B-type natriuretic peptide; EF = ejection fraction, LVMI = left ventricular mass index;

4. Table3. Forward stepwise multiple regression analysis of dependent variable
Total-Ad
HMW-Ad
Variables ｐ
HDL-C
0.394
0.000
0.356 Hb
-0.219
0.010
-0.180
0.034
log BNP
0.240
0.003
0.200
0.014
BMI
-0.235
0.009
-0.270
sex
0.237
0.004
0.289
0.001
Independent variables tested include age and sex, as well as parameters showing a
significant relationship in univariate analysis. β β