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A New Way to Diversify Antibodies by DNA Transposition

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Presentation on theme: "A New Way to Diversify Antibodies by DNA Transposition"— Presentation transcript:

1 A New Way to Diversify Antibodies by DNA Transposition
Davide F. Robbiani, Michel C. Nussenzweig  Cell  Volume 164, Issue 4, Pages (February 2016) DOI: /j.cell Copyright © 2016 Elsevier Inc. Terms and Conditions

2 Figure 1 Antibody Diversification by DNA Transposition
(A) Diagram of classical antibody proteins and antibody proteins containing a portion of LAIR1. Not to scale. (B) Candidate mechanisms to produce the LAIR1 fragment. Cryptic Recombination Signal Sequences (RSS) are represented by triangles in 1. DNA breaks are represented by arrows in 2. Not to scale. Cell  , DOI: ( /j.cell ) Copyright © 2016 Elsevier Inc. Terms and Conditions

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