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Is there a pharmacologic basis for combination renin axis blockade?

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Presentation on theme: "Is there a pharmacologic basis for combination renin axis blockade?"— Presentation transcript:

1 Is there a pharmacologic basis for combination renin axis blockade?
Norman K. Hollenberg  Kidney International  Volume 68, Issue 6, Pages (December 2005) DOI: /j x Copyright © 2005 International Society of Nephrology Terms and Conditions

2 Figure 1 Dose-response relationships. At dose X1 50% of a population shows the desired action (A), and at dose X2 50% of the same population shows an undesired action or side effect (B). Kidney International  , DOI: ( /j x) Copyright © 2005 International Society of Nephrology Terms and Conditions

3 Figure 2 Peak change in RPF are plotted in relation to eprosartan dose in subjects in balance on a low salt diet. Kidney International  , DOI: ( /j x) Copyright © 2005 International Society of Nephrology Terms and Conditions


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