1. Long-Term Outcomes After Surgical Resection of Pulmonary Metastases From Colorectal Cancer 
Hisashi Suzuki, MD, PhD, Moriyuki Kiyoshima, MD, Miyuki Kitahara, MD, Yuji Asato, MD, Ryuta Amemiya, MD, PhD 
The Annals of Thoracic Surgery 
Volume 99, Issue 2, Pages (February 2015)
DOI: /j.athoracsur
Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

2. Fig 1
Median follow-up period after pulmonary resection was 28.2 months (range, 1.1 to months), and the cumulative disease-specific survival after pulmonary resection was 45.5% at 5 years.
The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )
Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

3. Fig 2
(A) The 5-year survival of patients with colon (solid line) and rectal (dashed line) cancers was 62.4% and 33.8%, respectively, a difference that was significant (p = 0.030). (B) The 5-year survival of those with normal (solid line) and high (dashed line) preoperative carcinoembryonic antigen (CEA) levels was 57.0% and 30.9%, respectively, a difference that was significant (p = 0.038). (C) The 5-year survival of those with solitary (solid line) and multiple (dashed line) pulmonary metastases was 52.1% and 35.1%, respectively, a difference that was not significant (p = 0.058). (D) The 5-year survival of those with (+, dashed line) and without (–, solid line) a history of previously treated liver metastases (mets) was 46.2% and 45.6%, respectively, a difference that was not significant (p = 0.526).
The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )
Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

4. Fig 3
(A) Disease recurrence was identified in 65 of the 94 patients after pulmonary metastasectomy. Median interval between the pulmonary metastasectomy and disease recurrence was 11.5 months (range, 0–49.6 months), and disease-free survival after pulmonary resection was 20.7% at 5 years. (B) The disease-free survival of the high (dashed line) carcinoembryonic antigen (CEA) group was lower than that of the normal (solid line) CEA group, although the difference was not significant (p = 0.212).
The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )
Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

5. Fig 4
Distant metastasis developed in 55 patients after pulmonary metastasectomy. Among them, recurrence was limited to the liver or lungs, or both, in 39 patients. Of these 39 patients, 22 underwent surgical resection (solid line), 13 received nonsurgical treatment (small dashed line), and 4 were treated with palliative care (large dashed line). The 5-year survival after the first pulmonary resection was 75.6% for the surgical treatment group, 12.5% for the nonsurgical treatment group, and 0% for the palliative care group. The differences among these groups were significant (p < 0.001).
The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )
Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions