1. Study of the time course of the clinical effect of propofol compared with the time course of the predicted effect-site concentration: performance of three pharmacokinetic– dynamic models 
M. Coppens, J.G.M. Van Limmen, T. Schnider, B. Wyler, S. Bonte, F. Dewaele, M.M.R.F. Struys, H.E.M. Vereecke 
British Journal of Anaesthesia 
Volume 104, Issue 4, Pages (April 2010)
DOI: /bja/aeq028
Copyright © 2010 The Author(s) Terms and Conditions

2. Fig 1
The individual plasma- (dotted line) and effect-site concentrations (full line) vs time in Group M (Marsh's model) (a), Group S1 (Schnider's model with fixed ke0) (b), and Group S2 (Schnider's model with fixed TTPE) (c).
British Journal of Anaesthesia  , DOI: ( /bja/aeq028)
Copyright © 2010 The Author(s) Terms and Conditions

3. Fig 2
The individual BIS values vs time and their respective mean BIS values (sd) in Group M (Marsh's model) (a and b), Group S1 (Schnider's model with fixed ke0) (c and d), and Group S2 (Schnider's model with fixed TTPE) (e and f). ★Steady-state condition in BIS.
British Journal of Anaesthesia  , DOI: ( /bja/aeq028)
Copyright © 2010 The Author(s) Terms and Conditions