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Learning about Synaptic GluA3

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1 Learning about Synaptic GluA3
Zhengping Jia, Graham L. Collingridge  Neuron  Volume 93, Issue 2, Pages (January 2017) DOI: /j.neuron Copyright © 2017 Elsevier Inc. Terms and Conditions

2 Figure 1 GluA3-Mediated LTP at the PF-PC Synapse
Under basal condition, both GluA1/2 and GluA2/3 receptor types contribute to synaptic transmission. Upon LTP induction, the activation of cAMP/Epac signaling leads to increased single-channel conductance of GluA3-containing receptors, thereby enhancing synaptic transmission. The numbers of GluA1/2 and GluA2/3 AMPARs are not changed by LTP induction. Neuron  , DOI: ( /j.neuron ) Copyright © 2017 Elsevier Inc. Terms and Conditions

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